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PubMed COVID-19 Clinical Care

7041 - 7050 of 51970 results found

Transcriptional regulation of SARS-CoV-2 receptor ACE2 by SP1

Date
Tuesday, February 20, 2024 - 4:00 AM
Description
Angiotensin-converting enzyme 2 (ACE2) is a major cell entry receptor for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The induction of ACE2 expression may serve as a strategy by SARS-CoV-2 to facilitate its propagation. However, the

Anemoside B4 inhibits SARS-CoV-2 replication in vitro and in vivo

Date
Tuesday, February 20, 2024 - 4:00 AM
Description
CONCLUSION: Our results indicated that AB4 inhibited SARS-CoV-2 replication through the RLR pathways and moderated the RNA metabolism, suggesting that it would be a potential lead compound for the development of anti-SARS-CoV-2 drugs.