PubMed COVID-19 Clinical Care
12841 - 12850 of 51970 results found
Clinician and patient views on janus kinase inhibitors in the treatment of inflammatory arthritis: a mixed methods study
Description
CONCLUSION: JAKi are an effective treatment option for IA and are liked by patients. The COVID-19 pandemic appears to have impacted their prescription favourably. However, clinicians have safety concerns over JAKi use. Any decision to go on a JAKi
Socioeconomic impacts of airborne and droplet-borne infectious diseases on industries: a systematic review
Description
CONCLUSIONS: Evidence suggests that airborne and droplet-borne infectious diseases have inflicted severe socioeconomic costs on regional and global industries. Further research is needed to better understand their long-term socioeconomic impacts to
Evolution of enhanced innate immune suppression by SARS-CoV-2 Omicron subvariants
Description
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) human adaptation resulted in distinct lineages with enhanced transmissibility called variants of concern (VOCs). Omicron is the first VOC to evolve distinct globally dominant subvariants
How manufacturing won or lost the COVID-19 vaccine race
Description
The development of vaccines for COVID-19 occurred at an unprecedented pace, and 32 vaccines using a broad range of technologies had received authorization for use on an emergency basis by the end of 2021, from either a national regulatory authority
Effects of fear of COVID-19 on older volunteers' willingness to continue their activities: REPRINTS cohort study
Description
CONCLUSIONS: Our results suggest that the willingness of older adults to continue volunteer activities during the COVID-19 pandemic is influenced by their volunteer orientation and is not affected by their fear of COVID-19. Geriatr Gerontol Int 2024
Rational in silico design identifies two mutations that restore UT28K SARS-CoV-2 monoclonal antibody activity against Omicron BA.1
Description
SARS-CoV-2 rapidly mutates and acquires resistance to neutralizing antibodies. We report an in-silico-designed antibody that restores the neutralizing activity of a neutralizing antibody. Our previously generated antibody, UT28K, exhibited broad
Neutrophil degranulation, endothelial and metabolic dysfunction in unvaccinated long COVID patients
Description
CONCLUSION: In unvaccinated patients, symptoms may persist up to 1 year after acute COVID infection, with increased indices of neutrophil degranulation, endothelial and metabolic dysfunction. The clinical implications of specific inflammatory
Investigating the experiences of medical students quarantined due to COVID-19 exposure
Description
CONCLUSION: Supporting student wellbeing and learning is at the core of medical training. Enhanced understanding of health profession trainee needs during COVID can improve institutional supportive responses to students routinely and during times of
